- ￥2262
- LSM Bio
- 进口
- PAab07512
- 2025年07月15日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
R-spondin 3 homolog (Xenopus laevis)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
R-spondin 3 homolog (Xenopus laevis)
- 抗体英文名：
anti-RSPO3 antibody,RSPO3 antibody
- 抗体名：
anti-RSPO3 抗体,RSPO3 抗体
- 规格：
100μg
RSPO3抗体| RSPO3 antibody
货号 PAab07512
蛋白别名 PWTSR antibody, THSD2
蛋白介绍
Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors, which acts as a key regulator of angiogenesis. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta- catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway (PubMed:21727895, PubMed:21909076, PubMed:22615920). Acts as a key regulator of angiogenesis by controlling vascular stability and pruning: acts by activating the non-canonical Wnt signaling pathway in endothelial cells (By similarity).
产品描述
anti-RSPO3 antibody is a Rabbit Polyclonal antibody againstRSPO3..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using PAab07512( RSPO3 Antibody) at dilution of 1:200
Western blot
mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab07512( RSPO3 Antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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