- ￥2262
- LSM Bio
- 进口
- PAab07100
- 2025年07月15日
- ELISA,IHC,IF,IP,WB
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 文献和实验
- 技术资料
- 免疫原：
RAN, member RAS oncogene family
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,IHC,IF,IP,WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
RAN, member RAS oncogene family
- 抗体英文名：
anti-RAN antibody,RAN antibody
- 抗体名：
anti-RAN 抗体,RAN 抗体
- 规格：
100μg
RAN抗体| RAN antibody
货号 PAab07100
蛋白别名 ARA24
蛋白介绍
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
产品描述
anti-RAN antibody is a Rabbit Polyclonal antibody againstRAN..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using PAab07100( RAN Antibody) at dilution of 1:50
Western blot
HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab07100( RAN Antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验The GTPase RAN, the regulators of its nucleotide-bound state, and its effectors represent a specialized network in the RAS GTPase superfamily and regulate the localization of macromolecules (RNAs and proteins) in subcellular
High-resolution scanning electron microscopy provides three-dimensional surface images of nuclear pore complexes (NPCs) embedded in the nuclear envelope. Here, we describe a method for exposing the nuclear surface in mammalian
Cancer Res 重磅：丙二酰化修饰调控 Ran 蛋白，驱动前列腺癌进展与耐药
丙二酰辅酶A既是脂质从头合成的关键底物，也是线粒体脂肪酸β氧化的重要抑制分子。在脂质代谢异常驱动的恶性肿瘤中，它可能通过代谢物、蛋白翻译后修饰与信号通路之间的联动参与肿瘤进展。 前列腺癌是典型的脂质代谢重编程肿瘤，其进展与去势抵抗常伴随雄激素受体（AR）通路异常激活，但“代谢物—蛋白修饰—AR信号”之间的级联调控机制仍有待进一步解析。 郑州大学第一附属医院团队联合多家单位，在 Cancer Research 发表研究，围绕丙二酰辅酶A、MLYCD、Ran蛋白丙二酰化及AR信号开展系统研究，解析
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