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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform
- 抗体英文名:
anti-PPM1A antibody,PPM1A antibody
- 抗体名:
anti-PPM1A 抗体,PPM1A 抗体
- 规格:
100μg
PPM1A抗体| PPM1A antibody
货号 PAab06684
蛋白别名 PPPM1A
蛋白介绍
Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
产品描述
anti-PPM1A antibody is a Rabbit Polyclonal antibody againstPPM1A..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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文献和实验Coupling of Dephosphorylation and Nuclear Export of Smads in TGF- Signaling
to nucleus. We recently identified two important steps in the termination of nuclear Smad signaling. The first step is initiated by a serine/threonine phosphatase PPM1A that dephosphorylates Smad2/3 in the nucleus, thereby shutting down signaling capacity
手把手教你利用 CRISPR-Cas9 系统精准敲除靶标基因
3300 bps 大小的条带。8. 连接反应16 ℃ 过夜连接。敲除效率检测如果是敲人源细胞中的基因,我们可以在 293FT 细胞检测 系统的敲除效率,小鼠的细胞中的基因可以在 MEF 和 NIH3T3 中检测系统的敲除效率将上述 Px458M /Px459M-Guide RNA1 -Guide RNA2 转染进 293FT 细胞中 36 - 48 小时通过荧光显微镜和流式细胞仪检测转染效率提取转染细胞基因组,进行基因型鉴定。引物的设计方案如图 11 所示。图 12 显示敲除 PPM1A 基因。图
a PTPBAS C-term Antibody AP8446b DUSP16 C-term Antibody AP8466b PPEF2 C-term Antibody AP8413a PTPbeta C-term Antibody AP8446a DUSP16 N-term Antibody AP8454b PPM1A C-term Antibody AP8424a PTPD1 Center Antibody AP8434b DUSP3 C-term Antibody
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