- ￥2262
- LSM Bio
- 进口
- PAab06475
- 2025年07月15日
- ELISA,WB,IF,IHC,IP
- E. coli - derived recombinant protein
- Human, Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
piwi-like 1 (Drosophila)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IF,IHC,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
piwi-like 1 (Drosophila)
- 抗体英文名：
anti-PIWIL1 antibody,PIWIL1 antibody
- 抗体名：
anti-PIWIL1 抗体,PIWIL1 抗体
- 规格：
100μg
PIWIL1抗体| PIWIL1 antibody
货号 PAab06475
蛋白别名 HIWI
蛋白介绍
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation. Probable component of some RISC complex, which mediates RNA cleavage and translational silencing. Also plays a role in the formation of chromatoid bodies and is required for some miRNAs stability (By similarity). Isoform 3 may be a negative developmental regulator (PubMed:12037681, PubMed:16287078).
产品描述
anti-PIWIL1 antibody is a Rabbit Polyclonal antibody againstPIWIL1..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human testis tissue slide using PAab06475( PIWIL1 Antibody) at dilution of 1:50
Western blot
human testis tissue were subjected to SDS PAGE followed by western blot with PAab06475( PIWIL1 Antibody) at dilution of 1:600(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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