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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
deltex homolog 1 (Drosophila)
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9GZT9
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,IF,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
DTX1
- 抗体英文名:
anti-DTX1 antibody,DTX1 antibody
- 抗体名:
anti-DTX1 抗体,DTX1 抗体
- 规格:
100μg
DTX1抗体| DTX1 antibody
货号 PAab02553
蛋白别名
蛋白介绍
Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T- cell development, suggesting that it can antagonize NOTCH1.
产品描述
anti-DTX1 antibody is a Rabbit Polyclonal antibody againstDTX1..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途,不可用于临床诊断!)
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文献和实验
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