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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CCR4-NOT transcription complex, subunit 1
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9GZT9
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,IHC,WB,IP
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
CNOT1
- 抗体英文名:
anti-CNOT1 antibody,CNOT1 antibody
- 抗体名:
anti-CNOT1 抗体,CNOT1 抗体
- 规格:
100μg
CNOT1抗体| CNOT1 antibody
货号 PAab01805
蛋白别名 CDC39 antibody, KIAA1007 antibody, NOT1
蛋白介绍
Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA- mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3'UTRs. Involved in degradation of AU-rich element (ARE)-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A, TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintenance of emryonic stem (ES) cell identity.
产品描述
anti-CNOT1 antibody is a Rabbit Polyclonal antibody againstCNOT1..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human heart tissue slide using PAab01805( CNOT1 Antibody) at dilution of 1:200
Western blot
human brain tissue were subjected to SDS PAGE followed by western blot with PAab01805(CNOT1 antibody) at dilution of 1:800(本抗体仅供体外科研用途,不可用于临床诊断!)
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文献和实验
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