Rabbit Polyclonal Anti-ESR1 An

gene_symbol：ESR1
predicted_size：66 kDa
Uniprot ID：P3372
description：Rabbit Polyclonal Anti-ESR1 Antibody
clonality：Polyclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
immunogen：Fusion protein of human ESR1
recommended_dilution：WB: 200-1000 WB positive control: Mouse brain tissue, 231 and Hela cells
predicted_size：66 kDa
buffer：pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
host_species：Rabbit
applications：WB
reactivities：Human, Mouse, Rat