VEGF Receptor 1 (FLT1) mouse m

gene_symbol：FLT1
predicted_size：null
Uniprot ID：P17948
description：VEGF Receptor 1 (FLT1) mouse monoclonal antibody, clone FLTEWI (EWI), Purified
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes. VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity. Because sFLT1 has a higher affinity for VEGF than does FLK1, it may function as an inhibitor of VEGF response.
immunogen：Recombinant Human soluble extracellular Flt-1 protein (D5) (Cat.-No DA3539)
recommended_dilution：ELISA: 1-10 µg/ml. Western blotting: 1-10 µg/ml. Immunoprecipitation: 1-5 µg/ml lysate or reaction volume. Immunofluorescence. FACS: 2-10 μg/ml.
predicted_size：null
buffer：PBS; State: Purified; State: Lyophilized purified IgG fraction from Cell Culture Supernatant
host_species：Mouse
applications：ELISA, IF, IP, WB
reactivities：Human, Mouse