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文献和实验An In Vitro System to Evaluate the Scaffold Function of the RalA Effector Protein RalBP1
The in vitro kinase assay is an invaluable method to identify and characterize kinase substrates and to determine specific site(s) of phosphorylation. However, the use of recombinant proteins does not adequately account
中科院高福院士课题组 2020 年发表了哪些重要的研究成果?
抗体的主要靶标。2020 年 3 月 11 日,高福院士联合逯光文在 Cell Host & Microbe 发文:Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody。该研究报告了狂犬病毒 RABV-G 的晶体结构,分别在〜pH-8.0 时以游离形式和在〜pH-6.5 时与中和
for reporting both protein native mobility and binding specificity. Immunosubtraction is performed by removing antibody-bound target proteins from electrophoretic detection via a size-based exclusion filter, while unbound nontarget
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