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文献和实验Application of Functional Blocking Antibodies: N-Cadherin and Chick Embryonic Limb Development
The current trend in developmental biology research is to identify candidate functional genes and then manipulate their expression or activity by either gain or loss of function to elucidate the specific roles of their protein products
Using Cadherin Expression to Assess Spontaneous Differentiation of Embryonic Stem Cells
- to N-cadherin switch occurs during spontaneous differentiation of both murine and human ESCs. Here we describe the use of E-cadherin and N-cadherin proteins and transcript expression for assessing the proportion of undifferentiated and spontaneously
Neuronal Growth-Promoting and Inhibitory Cues in Neuroprotection and Neuroregeneration
that bind to CAMs on the surface of other axons or nonneuronal cells. In vitro assays have established the importance of the CAMs ((neural cell adhesion molecule NCAM), N-cadherin, and L1) in promoting axonal growth over cells. Compelling evidence implicates
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