PAN-HLA-II (DP- DQ- DR) ANTIBO

Characterization of HLA-DQ-Specific Peptide-Binding Motifs

peptide-binding motif (for a review see ref. 1 ). Such a motif can be used to predict whether a particular peptide will bind to a given HLA-molecule. The characterization of the peptide-binding motifs of disease-associated class II molecules

Mapping MHC Class II Genes and Disease-Susceptibility: Use of Polymerase Chain Reaction and Dot Hybridization for Human Leukocyte Antigen Allele Typin

into three regions, denoted class I, II, and III. The HLA class II gene complex is approx 1000 kb in length and is arranged into three main subregions (HLA-DP, −DQ, and −DR), each of which contains genes of two types, A and B. The A genes encode α-polypeptides and B

Typing Alleles of HLA-DM

for antigenic peptides. The genes encoding HLA-DM, HLA-DMA and -DMB , are located in tandem in the class II region of the MHC, between HLA-DP and HLA-DQ loci (1 ). HLA-DMA and -DMB products co-localize with HLA-DR in the specialized acidic MHC class II