NEUN MABMA548808

Localization of the Cyclic Guanosine 3,5-Monophosphate- Hydrolyzing Phosphodiesterase Type 9 in Rat Brain by Nonradioactive In Situ Hybridization

hybridization (ISH). The three different riboprobes used all showed similar PDE9 mRNA expression patterns, detecting PDE9 in cell bodies throughout the whole brain. By using immunocytochemical double labeling of the ISH sections with the neuronal marker NeuN

Immunocytochemical Analysis of Neuronal Differentiation

Doublecortin (Dcx), the early expressed marker Hu, and mature neuronal marker NeuN. In Chapters 25 and 27 of Part IV, we provide protocols for identifying newborn cells by using the mitotic label bromodeoxyuridine and for examining axonal projections by using

Science：保护好你的肝，运动让大脑更年轻的奥秘在这里！

对老龄小鼠海马的这些影响是否可以通过施用运动诱发的循环血液因子来转移？研究者通过向老龄小鼠静脉注射运动或久坐的老龄小鼠血浆，在 3 周内注射 8 次。研究通过免疫组织化学的方法分析了小鼠的神经发生。研究发现，在给予运动小鼠血浆后海马齿状回新生神经元含有双皮质素（DCX，被认为是未成熟神经元的经典标志物）蛋白的数量增加。研究通过 5 - 溴 - 2 - 脱氧尿苷（BrdU）评估神经元分化。成熟分化的神经元同时表达 BrdU 和成熟神经元标记 Neun。在齿状回表达 BrdU 和 NeuN 的成熟神经