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文献和实验Natural Killer Cell Reprogramming with Chimeric Immune Receptors
Natural killer (NK) cells are emerging as a new tool for cell therapy of cancer. However, some cancer subtypes are relatively resistant to NK cell cytotoxicity. Expression of anti-CD19 chimeric signaling receptors can enhance NK-cell
Construction and Purification of Adhesion Molecule Immunoglobulin Chimeric Proteins
for the identification and purification of ligands to all three known selectins, including the L-selectin ligands GlyCAM-1 and CD34, the E-selectin ligand ESL-1, and finally the P-selectin ligand PSGL-1 (2 –6 ). In addition, such adhesion molecule-Ig chimeras
membrane, creating a structure similar to an ion channel Delivers early signal in B cell activation, allowing resting B cells to respond to later antigens Rituximab is a chimeric murine-human anti-CD20 antibody used for treatment of B cell
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