- ￥6125
- 赛默飞（Thermo Fisher）
- MA547558
- 2025年07月14日
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文献和实验Clostridium difficile Toxinotyping
Clostridium difficile shows considerable variability in the PaLoc region encoding two main virulence factors, toxins TcdA and TcdB. Strains with changes in PaLoc are defined as variant toxinotypes and currently 27 such groups are recognized
Transposon Mutagenesis in Clostridium difficile
Genetic manipulation of Clostridium difficile is notoriously difficult, currently there is only one reliable method for generating random mutations in the organism and that is to use the conjugative transposon Tn916 . Tn916 enters the genome
Clostridium difficile and the Disease It Causes
Clostridium difficile is a spore-forming, toxin-producing, anaerobic bacterium abundant in soils and water. Frequent and early colonization of the human intestinal flora is common and often asymptomatic. Antimicrobials given commonly disrupt
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