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文献和实验腺苷酸激酶 adenylate kinase 催化腺苷三磷酸( ATP)使腺苷酸( AMP)磷酸化而生成腺苷二磷酸( ADP)反应的酶, EC 2. 7. 4. 3.逆反应由 2个分子 ADP生成 ATP和 AMP。 最初为科洛韦克和卡尔查尔( S. P. Colowick andH. M. Kalckar, 1943)在肌肉中发现,称为肌激酶。已知在肝脏、肾脏、微生物中都存在。脱氧腺苷酸也可以作为底物。此酶特别稳定
Analysis of the Role of the AMP-Activated Protein Kinase in the Response to Cellular Stress
of the ADP:ATP ratio, due to the action of adenylate kinase which maintains its reaction (2ADP ’ ATP + AMP) close to equilibrium at all times. Therefore, any cellular stress that affects the ability of the cell to maintain a high ATP: ADP ratio (normally
Preparation of Recombinant Protein Spotted Arrays for Proteome‐Wide Identification of Kinase Targets
allow unique approaches for interrogating global protein interaction networks. Protein arrays can be divided into two categories: antibody arrays and functional protein arrays. Antibody arrays consist of various antibodies and are appropriate
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