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文献和实验Semiquantitative PCR for the Detection of Exon Rearrangements in the Parkin Gene
Mutations in the parkin gene have been shown to be responsible for a substantial number of cases of autosomal recessive early onset parkinsonism (AR-JP, PARK2, OMIM 602544) worldwide (1 –4 ). The gene on chromosome 6q25.2-27 consists of 12
Parkinsons Disease: Assays for the Ubiquitin Ligase Activity of Neural Parkin
The identification of monogenic variants of Parkinson’s disease (PD) has provided novel insights into its unknown pathogenesis. As the first protein linked to autosomal-recessive forms of PD, Parkin became a welcome tool to explain
Anti-factor Xa (Anti-Xa) Assay
The anti-factor Xa (anti-Xa) assay is a functional assay that facilitates the measurement of antithrombin (AT)-catalyzed inhibition of factor Xa by unfractionated heparin (UFH) and direct inhibition of factor Xa by low-molecular-weight
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