4-Hydroxy Atorvastatin Calcium

1) Cat. No.: TRC-H828961; 2) Chemical Name: 4-Hydroxy Atorvastatin Calcium Salt; 3) CAS No.: ; 4) Mol. Formula: C33H33CaFN2O6; 5) Mol. Weight: 612.7; 6) Packing Size: 1mg / 10mg; 7) Appearence: Light Beige Solid; 8) Application Notes: 4-Hydroxyatorvastatin is a hydroxylated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.; 9) Synonym: (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-4-[[(4-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrole-1-heptanoic Acid Calcium Salt; p-Hydroxyatorvastatin Calcium Salt; ; 10) Solubility: Methanol; 11) Storage condition: Hygroscopic, -20˚C Freezer, Under Inert Atmosphere; 12) References: Smith, S. et al.: Am. J. Cardiol., 80, 10H (1997); Jacobsen, W. et al.: Drug Metab. Dispos., 28, 1369 (2000); Istvan, E. et al.: Science, 292, 1160 (2001); Tabernero, L. et al.: J. Biol. Chem., 278, 19933 (2003); Bratton, L. et al.: Bioorg. Med. Chem., 15, 5576 (2007);