- ￥5016
- BioLegend-HK
- 948606
- 美国
- 2025年07月13日
- 免疫荧光，流式
- 大鼠
- Human, Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
Alexa Fluor® 647 anti-GATA4
- 抗体英文名：
Alexa Fluor® 647 anti-GATA4
- 应用范围：
免疫荧光，流式
- 宿主：
大鼠
- 供应商：
上海善然生物
- 库存：
4-5周
- 抗原来源：
大鼠
- 保质期：
2-3年左右
- 适应物种：
Human, Mouse
- 标记物：
Alexa Fluor® 647
- 克隆性：
单克隆
- 保存条件：
2-8度
- 形态：
液体
- 规格：
100 tests
Alexa Fluor® 647 anti-GATA4 Antibody
W19078B
Catalog# / Size 948605 / 25 tests
948606 / 100 tests
Clone
Regulatory Status RUO
Other Names GATA-binding factor 4, GATA-4, TACHD, ASD2, VSD1, TOF
Isotype Rat IgG2a, κ
Description GATA binding protein 4 (GATA4) is a zinc-finger transcription factor that plays a crucial role in
transcriptional activation and cell growth, differentiation, survival, and senescence. It is essential
to cardiac development and function. Along with GATA6, it modulates cardiac stress response and
regulates cardiomyocyte formation, replication, and function. GATA4 participates in second heart
field transcription and differentiation and ventricular morphogenesis through downstream
regulation of Mef2c and Hand2. Mutations in GATA4 can result in myocardial abnormalities,
myocardial hypoplasia, absence of a proepicardium, abnormal valve formation, and endocardial
cushion defects. In the intestine, GATA4, along with GATA6, is also responsible for regulating
epithelial cytodifferentiation and structure, and for maintaining balance between enterocytes and
secretory cells through the coordination of Notch signaling. GATA4 plays a vital role in human
testicular development through its regulation of the expression of steroidogenic factors StAR,
INHA, HSD3B2, and CYP19A1 and sex-determining genes SRY, AMH, and SOX9.
Product Details
Verified Reactivity Human, Mouse
Antibody Type Monoclonal
Host Species Rat
Immunogen Recombinant human GATA4 protein
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under
optimal conditions.
Concentration Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our
Certificate of Analysis online tool.)
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged
exposure to light. Do not freeze.
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文献和实验更多产品详细信息欢迎来电咨询~周祥15900853496微信同号，汪海洋15901695283微信同号 BioLegend-HK
的耐光性和良好的荧光量子产量著称。因此很多Alexa Fluor® 染料具有罗丹明核心结构，但是，传统罗丹明的化学结构很难从长波长的荧光染料延伸至远红外区域甚至是更具挑战性的近红外区域，而且生物偶联后其水溶性并不理想。Biotium 科学家发现从绿色到近红外多色荧光的罗丹明染料的新型化学方法。该方法被有效的应用于CF染料的产品中，尤其是远红外CF染料，而且通过这种方法制备的染料不仅水溶性极佳而且耐光性极好。图1. CF系列染料的稳定性，图示为CF633在5min中仍然具有稳定的荧光强度；而AF647
技术原理与方法｜超级色差校正物镜 PLAPON60XOSC 在脑组织四重免疫荧光分析中的应用
种类型的荧光抗体在单个标本中准确展示荧光标记分子的共定位情况。 PLAPON60XOSC 和 UPLSAPO60XO 的性能比较 2. 超级色差校正物镜的应用-脑组织的四重免疫荧光 图 1. 脑组织的四重免疫荧光。 VIAAT 染色（Alexa Fluor405，蓝色）；CB1 染色（Alexa Fluor488，绿色）；VGluT3 染色（Cy3，红色）；DGLα染色（Alexa Fluor647，白色）。 大麻素合成酶 DGLα（白色）和大麻素受体 CB1（绿色）聚集在小鼠
'）2 Fragment（Alexa Fluor® 555 Conjugate）#4413 Anti-Rabbit IgG（H+L）， F（ab'）2 Fragment（Alexa Fluor® 647 Conjugate）#4414 抗小鼠： Anti-Mouse IgG（H+L）， F（ab'）2 Fragment（Alexa Fluor® 488 Conjugate）#4408 Anti-Mouse IgG（H+L）， F（ab'）2 Fragment（Alexa Fluor
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