- ￥2437
- BioLegend
- 353202
- 美国
- 2025年07月16日
- 免疫荧光，流式
- 小鼠
- Human Reported Reactivity African Green, Baboon, Cynomolgus, Rhesus
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- 抗体名：
Purified anti-human CD197 (CCR7)
- 抗体英文名：
Purified anti-human CD197 (CCR7)
- 浓度：
0.5 mg/mL
- 应用范围：
免疫荧光，流式
- 宿主：
小鼠
- 供应商：
上海善然生物
- 库存：
现货
- 抗原来源：
小鼠
- 保质期：
2-3年左右
- 适应物种：
Human Reported Reactivity African Green, Baboon, Cynomolgus, Rhesus
- 标记物：
Purified
- 克隆性：
单克隆
- 形态：
液体
- 规格：
100 μg
Purified anti-human CD197 (CCR7) Antibody
G043H7
Catalog# / Size 353202 / 100 µg
Clone
Regulatory Status RUO
Other Names BLR2, CDw197, EBI1, CMKBR7
Isotype Mouse IgG2a, κ
Description CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7
and its ligands link innate and adaptive immunity by affecting interactions between T cells and
dendritic cells and their downstream effect. Naïve T cells enter the lymph node through high
endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph
node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell
zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate
between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs,
surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to
interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-
positive cancer cell expression has been associated with lymph node metastasis.
Version: 3 Revision Date: 08/25/2022
Product Details
Verified Reactivity Human
Reported Reactivity African Green, Baboon, Cynomolgus, Rhesus
Antibody Type Monoclonal
Host Species Mouse
Immunogen CCR7-transfected cells
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography.
Concentration 0.5 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C
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