InvivoCrown In vivo PD-L1 bloc

InVivoPro Anti-Mouse PD-L1(B7-H1, CD274) in vivo antibody, Clone 10F.9G2InVivoPro Anti-Mouse PD-L1(B7-H1, CD274) in vivo antibody, Clone 10F.9G2Rat IgG2b κRat IgG2b κ10F.9G210F.9G2PD-L1PD-L1Programmed cell death ligand 1，B7-H1，CD274，PD-L1Programmed cell death ligand 1，B7-H1，CD274，PD-L1IV0106 or Rat IgG2b Isotype Control IV0106 or Rat IgG2b Isotype Control PBS, pH 7.2, contains no stabilizers or preservativesPBS, pH 7.2, contains no stabilizers or preservativesMouseMouseRatRat200-500 μg per mouse; or 10 mg/kg. This range is based off the most recent publication data using the 10F.9G2 clone in vivo. Each investigator should determine their own optimal working dilution for specific applications.200-500 μg per mouse; or 10 mg/kg. This range is based off the most recent publication data using the 10F.9G2 clone in vivo. Each investigator should determine their own optimal working dilution for specific applications.483483Spitzer, Matthew H., et al. "Systemic immunity is required for effective cancer immunotherapy." Cell 168.3 (2017): 487-502. Poggio, Mauro, et al. "Suppression of exosomal PD-L1 induces systemic anti-tumor immunity and memory." Cell 177.2 (2019): 414-427. Balood, Mohammad, et al. "Nociceptor neurons affect cancer immunosurveillance." Nature 611.7935 (2022): 405-412.Spitzer, Matthew H., et al. "Systemic immunity is required for effective cancer immunotherapy." Cell 168.3 (2017): 487-502. Poggio, Mauro, et al. "Suppression of exosomal PD-L1 induces systemic anti-tumor immunity and memory." Cell 177.2 (2019): 414-427. Balood, Mohammad, et al. "Nociceptor neurons affect cancer immunosurveillance." Nature 611.7935 (2022): 405-412.CD274, also known as B7-H1 and PD-L1, is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes.CD274, also known as B7-H1 and PD-L1, is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes.In vivo PD-L1 blockedIn vivo PD-L1 blockedprotein A or Gprotein A or GThis antibody is stable for at least 2 months when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C or -80°C. Avoid repeated freeze thaw cycles.This antibody is stable for at least 2 months when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C or -80°C. Avoid repeated freeze thaw cycles.2-8°C with blue ice2-8°C with blue iceLot specific, generally ≥ 5.0 mg/mlLot specific, generally ≥ 5.0 mg/ml12 months from the date of receipt if stored as recommended12 months from the date of receipt if stored as recommendedPBS Buffer, PH 7.2, with no carrier protein, or preservatives.PBS Buffer, PH 7.2, with no carrier protein, or preservatives.0.2 μM filtered0.2 μM filtered≤ 1.0 EU/mg, by the LAL method≤ 1.0 EU/mg, by the LAL method0.990.99可替换BioXCell产品货号为BE0101