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- 技术资料
- 抗体名:
APC anti-mouse IL-17RB
- 抗体英文名:
APC anti-mouse IL-17RB
- 浓度:
0.2 mg/ml
- 应用范围:
免疫荧光,流式
- 宿主:
大鼠
- 供应商:
上海善然生物
- 库存:
现货
- 抗原来源:
大鼠
- 保质期:
2-3年左右
- 适应物种:
小鼠
- 标记物:
APC
- 克隆性:
单克隆
- 保存条件:
2-8度
- 形态:
液体
- 规格:
25ug
APC anti-mouse IL-17RB Antibody
9B10
Catalog# / Size 146307 / 25 µg
146308 / 100 µg
Clone
Regulatory Status RUO
Other Names Evi27, IL-17ER, IL17RH1, IL17br, IL-17 receptor B
Isotype Rat IgG2a, κ
Description IL-17RB, also known as IL17RH1, belongs to the cytokine receptor family. IL-17RB
possesses a unique intracellular signaling molecule called SEFIR, and is expressed similarily
to fibroblast growth factor genes and IL-17R. It is reported to be expressed on iNKT cells,
innate lymphoid cells (ILC), and Th2 cells. It binds IL-17B and IL-17E (IL-25) but not IL-17A or
C. Its interaction with IL-25 has a higher affinity than that with IL-17B. Binding of IL-17RB and
IL-25/IL-17E induces NF-kB mediated IL-8 production through interaction with TRAF6 and
Act1. IL-17RB has been reported to play a role in autoimmune diseases such as rheumatoid
arthritis and asthma.
Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Immunogen Recombinant mouse IL-17RB - Fc chimera (human IgG1)
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography and conjugated with APC under optimal
conditions.
Concentration 0.2 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not freeze.
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