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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
APC/Cyanine7 anti-mouse CD172a (SIRPα)
- 抗体英文名:
APC/Cyanine7 anti-mouse CD172a (SIRPα)
- 浓度:
0.2 mg/ml
- 应用范围:
免疫荧光,流式
- 宿主:
大鼠
- 供应商:
上海善然生物
- 库存:
现货
- 抗原来源:
大鼠
- 保质期:
2-3年左右
- 适应物种:
小鼠
- 标记物:
APC/Cyanine7
- 克隆性:
单克隆
- 保存条件:
2-8度
- 形态:
液体
- 规格:
100 μg
APC/Cyanine7 anti-mouse CD172a (SIRPα) Antibody
P84
Catalog# / Size 144017 / 25 µg
144018 / 100 µg
Clone
Regulatory Status RUO
Other Names SHPS-1, BIT, P84, PTPNS1, CD172 antigen-like family member A
Isotype Rat IgG1, κ
Description CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and
two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich
region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid
cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and
activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative
regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.
Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Immunogen Mouse brain membrane protein
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under
optimal conditions.
Concentration 0.2 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not freeze.
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