- ￥4945
- BioLegend
- 124324
- 美国
- 2025年07月14日
- 免疫荧光，流式
- 大鼠
- 小鼠
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
PE/Dazzle™ 594 anti-mouse CD274 (B7-H1, PD-L1)
- 抗体英文名：
PE/Dazzle™ 594 anti-mouse CD274 (B7-H1, PD-L1)
- 浓度：
0.2 mg/ml
- 应用范围：
免疫荧光，流式
- 宿主：
大鼠
- 供应商：
上海善然生物
- 库存：
现货
- 抗原来源：
大鼠
- 保质期：
2-3年左右
- 适应物种：
小鼠
- 标记物：
PE/Dazzle™ 594
- 克隆性：
单克隆
- 保存条件：
2-8度
- 形态：
液体
- 规格：
100 μg
PE/Dazzle™ 594 anti-mouse CD274 (B7-H1, PD-L1) Antibody
10F.9G2
Catalog# / Size 124323 / 25 µg
124324 / 100 µg
Clone
Regulatory Status RUO
Other Names B7-H1, PD-L1
Isotype Rat IgG2b, κ
Description CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I
transmembrane protein and a member of the B7 family within the immunoglobulin receptor
superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated
endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-
H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have
shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is
involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in
an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell
proliferation and cytokine production.
Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under
optimal conditions.
Concentration 0.2 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not freeze.
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[J]． EMBO J, 1992,11(11):3887-2895. [2] Okazaki T, Wang J. PD-1/PD-L pathway and autoimmunity [J].Autoimmunity, 2005,38(5):353-357. [3] Okudaira K, Hokari R, Tsuzuki Y, et al． Blockade of B7-H1 or B7-DC induces an anti-tumor effect in a mouse
of genetics, the mouse has become a widely used animal model in vision research. However, its eyeball has an axial length of only about 2 mm. The present protocol describes how to easily dissect the small rodent eye post mortem. This allows collecting
) A431 cells. At 48 h after infection, these cells were stained with ten different primary antibodies (5 g/ml) specific for different cell surface markers: anti-CD15 (clone 2F3; BD, PharMingen, San Diego, CA), anti-ERBB-2 (clone SP77; ref. 5), anti-ERBB
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