重组人音猬因子（Shh）

重组人音猬因子（Shh） Human Sonic Hedgehog Protein

产品编号：PRP1032

核心参数

• 种属来源：人源（Homo sapiens）
• 表达系统：大肠杆菌表达系统
• 蛋白结构：176个氨基酸组成，含N端His标签
• 分子量测定：23.48 kDa（理论预测值）
• 纯度验证：SDS-PAGE检测纯度>98%
• 内毒素控制：EU含量<1.0/μg（LAL法检测）

产品规格与订购

规格	价格（RMB）	货期
20 µg	1,498	现货
100 µg	4,698	现货
1 mg	12,998	定制生产（联系获取交期）

质量控制

• 物理形态：冻干粉末制剂
• 缓冲体系：无菌PBS（pH7.5）冻干保护剂
• 复溶建议：推荐使用配套复溶缓冲液

存储与运输

• 长期保存：-20℃以下干燥环境
• 复溶后保存：4℃稳定2-7天，长期保存需-20℃
• 运输保障：专业冷链包装（蓝冰运输）

重要实验提示

• 使用前需离心处理冻干粉
• 避免反复冻融影响蛋白活性

分子生物学信息

• UniProt ID：Q15465
• Gene ID：6469
• 蛋白序列：人源SHH（Gly25-Gly197）

应用背景

Sonic Hedgehog（SHH）作为Hedgehog信号通路核心成员，在胚胎发育调控中发挥关键作用，涉及神经管模式形成、肢体发育及器官发生等过程。研究表明SHH信号异常与多种肿瘤发生发展密切相关，包括基底细胞癌、髓母细胞瘤等。

重要声明：

本产品仅限于科研用途，不可用于临床诊断或治疗用途。使用前请充分了解并遵守相关生物安全法规及知识产权规定。

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注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Recombinant Human Sonic Hedgehog Protein (Shh)

Product Number: PRP1032

Key Parameters

• Species Source: Human (Homo sapiens)
• Expression System: E. coli Expression System
• Protein Structure: 176 amino acids, with N-terminal His-tag
• Molecular Weight Determination: 23.48 kDa (Theoretical Prediction)
• Purity Verification: >98% by SDS-PAGE
• Endotoxin Control: EU Content <1.0/μg (LAL Assay)

Product Specifications & Ordering

Specification	Price (RMB)	Lead Time
20 µg	1,498	In Stock
100 µg	4,698	In Stock
1 mg	12,998	Custom Production (Contact for Lead Time)

Quality Control

• Physical Form: Lyophilized Powder
• Buffer System: Sterile PBS (pH7.5) with Lyoprotectant
• Reconstitution Recommendation: Use the provided reconstitution buffer

Storage & Shipping

• Long-term Storage: Below -20°C in a dry environment
• Post-reconstitution Storage: Stable at 4°C for 2-7 days, long-term storage at -20°C
• Shipping Assurance: Professional cold chain packaging (Blue Ice Shipping)

Important Experimental Tips

• Centrifuge the lyophilized powder before use
• Avoid repeated freeze-thaw cycles to maintain protein activity

Molecular Biology Information

• UniProt ID: Q15465
• Gene ID: 6469
• Protein Sequence: Human SHH (Gly25-Gly197)

Application Background

Sonic Hedgehog (SHH), as a core member of the Hedgehog signaling pathway, plays a crucial role in embryonic development regulation, including neural tube patterning, limb development, and organogenesis. Recent studies have shown that abnormal SHH signaling is closely related to the development of various tumors, including basal cell carcinoma and medulloblastoma.

Important Notice:

This product is for research use only and is not intended for clinical diagnosis or therapeutic use. Please fully understand and comply with relevant biosafety regulations and intellectual property rights before use.

Note: The above information may be subject to change due to product optimization and upgrades. For specific information, please consult Abbkine Company.