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huayun / PDGF-BB/ PDGF2 (C-6Hi

s), Mouse, Recombinant,HYPC5084
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  • ¥4140
  • 华韵生物(Huayunbio)
  • HYPC5084
  • 2025年07月14日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      广州华韵生物科技有限公司

    • 规格

      10µg

    产品信息

    别名PDGFBB; PDGF-BB
    物种Mouse
    表达宿主E.coli
    序列信息 Ser82-Thr190
    检索号AAH53430.1
    分子量13.4 kDa
    表观分子量15 KDa, reducing conditions

    产品特性

    纯度 >95% as determined by reducing SDS-PAGE.
    内毒素< 1.0 EU per µg as determined by LAL test.
    保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2~8℃ for 2~7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输 Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in 4mM HCl.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    背景介绍

    Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/ VEGF Growth Factor family. Platelet-Derived Growth Factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-Derived Growth Factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As Growth Factor,it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. PDGFB also plays an important role in wound healing.

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