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huayun / PDGF-BB/ PDGF2, Human

, Recombinant,HYPC5083
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  • ¥5340
  • 华韵生物(Huayunbio)
  • HYPC5083
  • 2025年07月07日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      广州华韵生物科技有限公司

    • 规格

      10µg

    产品信息

    别名PDGFBB; PDGF-BB
    物种Human
    表达宿主E.coli
    序列信息Ser82-Thr190
    检索号P01127
    分子量12.42 kDa
    表观分子量14 kDa
    生物活性 Measured in a cell proliferation assay using BALB/c 3T3 cells. The ED50 for this effect is 5-20 ng/ml.

    产品特性

    纯度 >95% as determined by reducing SDS-PAGE.
    内毒素< 1.0 EU per µg as determined by LAL test.
    保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2~8℃ for 2~7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输 Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    背景介绍

    Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/ VEGF Growth Factor family. Platelet-Derived Growth Factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-Derived Growth Factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its Receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

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    图标文献和实验
    相关实验
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    • Intraspinal Transplantation of Mouse and Human Neural Precursor Cells

      the preparation and transplantation of human neural precursor cells (hNPCs) and mouse neural precursor cells (mNPCs) into the thoracic region of the mouse spinal cord. The techniques in this unit also describe how to prepare the mouse for surgery by performing

    • 细胞因子的分类

      )、MIllp、正常T细胞激活上调性表达因子(RANTES)、单核细胞趋化蛋白―1(MCP-1/MCAF)、MCP-2、MCP-3和1-309等;③C-X3―C亚族,只有一个成员Fractalkine;④XC亚族,目前发现有淋巴细胞趋化因子(1vmphotactin,LTN)和SCM-1日两个成员。     7.其他细胞因子  如表皮生长因子(EGF)、血小板衍生生长因子(PDGF)、成纤维细胞生长因子(FGF)、肝细胞生长因子(HGF)、胰岛素样生长因子―I(1GF-1)和IGF-Ⅱ、白血

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