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huayun / M-CSF/ CSF1, Mouse, R

ecombinant,HYPC5062
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  • ¥5340
  • 华韵生物(Huayunbio)
  • HYPC5062
  • 2025年07月12日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      广州华韵生物科技有限公司

    • 规格

      10µg

    产品信息

    别名Macrophage colony-stimulating factor 1; CSF-1; MCSF; Csf1; Csfm
    物种Mouse
    表达宿主Human Cells
    序列信息Lys33-Glu262
    检索号P07141
    分子量26.0 kDa
    表观分子量37-80kDa
    生物活性 Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells.The ED50 for this effect is 0.04-0.2 ng/ml.

    产品特性

    纯度 >95% as determined by reducing SDS-PAGE.
    内毒素<1.0 EU per µg as determined by LAL test.
    保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2~8℃ for 2~7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输 Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    背景介绍

    Macrophage colony-stimulating factor 1 (M-csf)is a single-pass type I membrane Protein . It is a hematopoietic Growth Factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/ macrophage cell lineage. By interacting with its membrane Receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.

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