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文献和实验in this study can obtain cochlea mi-crovascalar endothelial cells of guinea pig in vitro. Key words : endothelium cell ; cell , cultured ; capillaries ; cochlea 血迷路屏障是存在于血液与内耳迷路液之间、具有选择性通透功能的生理屏障系统,其作用在于保持迷路液成分的相对稳定,维持内耳微环境的平衡,从而保证内耳感音装置行使正常
Overview of Receptor Allosterism
Figure 1.21.9 Effect of the allosteric modulators gallamine and alcuronium on the binding of the orthosteric antagonist, [3 H] N ‐methylscopolamine, at M2 muscarinic acetylcholine receptors in guinea pig atrial membranes
Saturation Assays of Radioligand Binding to Receptors and Their Allosteric Modulatory Sites
. Radioligand binding (in this case, 5 nM [3 H](+)‐pentazocine binding to the sigma receptor in guinea‐pig brain) increases exponentially with time, becoming maximal after 60 min. Based on this data, equilibrium binding assays employing this radioligand
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