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流式抗体/ AF/LE Purified Anti-Huma

n CD279/PD-1 Antibody[J110],HFC3685-500μg
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  • ¥5135
  • 华韵生物(Huayunbio)
  • HFC3685-500μg
  • 2025年07月14日
  • FCM
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保质期

      12个月

    • 供应商

      广州华韵生物科技有限公司

    • 应用范围

      FCM

    • 规格

      500μg

    温馨提示:产品由于优化升级,可能会增删改替。内容请以实时说明书信息为准。
    请联系华韵客服获取说明书。

    产品简介:

     

    Background
    Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
    Alternate Names
    PD1;PDCD1;Protein PD-1;hPD-1
    Swissprot
    Q15116
    Gene ID
    5133
    Clone No
    J110
    Host
    Mouse
    Reactivity
    Human
    Application
    FCM
    Isotype
    Mouse IgG1, κ
    Isotype Control
    AF/LE Purified Mouse IgG1, κ Isotype Control[MOPC-21]
    Conjugation
    None (AF/LE)
    Storage Buffer
    0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
    Storage
    This product can be stored at 2-8°C for 12 months. Do not freeze.
    Expiration date
    12个月
    Shipping
    冰袋

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    图标文献和实验
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