Mouse TGF-β3 (Transforming Gro

Transforming Growth Factor-: A Key Mediator of Fibrosis

Transforming growth factor (TGF)-β is a prototypic multifunctional cytokine whose broad modulatory mechanisms affect numerous biological functions both at the cell and organism levels. These include, but are not limited to, control of immune

Detection of the Transcripts and Proteins for the Transforming Growth Factor- Isoforms and Receptors in Mouse Lung Tumorigenesis Using In Situ Hybridi

Several critical polypeptide growth factors have been identified for the lung, including transforming growth factor-beta (TGF-β). The three mammalian TGF-β isoforms, TGF-β1, TGF-β2, and TGF-β3, are homologous growth mediators

Hammerhead Ribozyme-Mediated Knockdown of mRNA for Fibrotic Growth Factors: Transforming Growth Factor-Beta 1 and Connective Tissue Growth Factor

Excessive scarring (fibrosis) is a major cause of pathologies in multiple tissues, including lung, liver, kidney, heart, cornea, and skin. The transforming growth factor-β (TGF-β) system has been shown to play a key role in regulating