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文献和实验Embryonic Stem Cells as a Model for Studying Osteoclast Lineage Development
are found tightly attached to bone matrix ( 1 , 2 ). Two cytokines, macrophage colony-stimulating factor (M-CSF) and receptor activator of NF-κB (RANK) ligand (RANKL; also known as OPGL, ODF, and TRANCE), are known to be responsible for this differentiation ( 5 –
and tumor cells (1 –3 ). The nomenclature for the members of the TNF superfamily was becoming complicated; individual members were given different names, e.g., Fas ligand, CD95 ligand, APO-1 ligand, by the competing research groups involved
TRAF‐Mediated TNFR‐Family Signaling
differentiation factor osteoprotegerin‐ligand is essential for mammary gland development. Cell 103:41‐50. Feng, X., Gaeta, M.L., Madge, L.A., Yang, J.H., Bradley, J.R., and Pober, J.S
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