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文献和实验Expression of Neurotrophic Factors such as GDNF in the E. coli System
neurotrophic factor (BDNF), neurotrophin-3 (NT-3), NT-4/5, glial-cell-line-derived neurotrophic factor (GDNF), ciliary neurotrophic factor (CNTF), insulin-like growth factor-1 (IGF-I), are currently in clinical trials and have potential
GDNF Maintains Mouse Spermatogonial Stem Cells In Vivo and In Vitro
-derived neurotrophic factor (GDNF) in a dose-dependent manner. After this in vivo observation, the culture conditions for mouse SSCs were rapidly developed. GDNF together with other growth factors, hormones, and vitamins maintain proliferation and self
脂肪燃烧的指令从哪里来?Nature 揭示神经免疫互作如何与
表明神经-间充质细胞之间的信号能够调节内脏脂肪的 ILC2s。图片来源:Nature间充质来源的 GDNF(glial-derived neurotrophic factor)调控 ILC2s为了研究神经-间充质相互作用是如何调节 ILC2s 的激活,他们对来自 6-OHDA 处理小鼠和对照组小鼠的 PDGFRA 阳性 MSCs 进行了全转录组分析。发现 Gdnf 在 PDGFRA 阳性 MSCs 中高表达,而 6-OHDA 处理则可显著降低其表达。与上述结果一致的是,Adrb2 敲除小鼠的内脏
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