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文献和实验Platelet Receptor Structures and Polymorphisms
Efficient platelet cohesion (i.e., platelet aggregation) is necessary for the life-saving process of hemostasis. Plaque rupture and/or endothelial damage lead to exposure of collagens, retention of von Willebrand factor (vWF
Molecular Biological Identification and Characterization of Inherited Platelet Receptor Disorders
, polyploid cells demarcate their cytoplasm, giving rise to circulating platelets. Following vascular injury, platelets adhere to the site of injury through von Willebrand factor (vWF) and the platelet membrane glycoprotein (GP) Ib/IX complex. The platelets
对儿茶酚胺反应的受体,有α和β二类,α受体是其中一种。α受体一般表现兴奋性反应,儿茶酚胺与α受体作用可引起血管、子宫、输精管等的平滑肌收缩。阻断这一反应的药物为α阻断剂,有麦角碱、地苯那明(Dibenamine,双苄胺)、苯氧基苯胺等。
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