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文献和实验A Rapid Analysis of Human Paraoxonase Gene Cluster Polymorphism
A Rapid Analysis of Human Paraoxonase Gene Cluster Polymorphism 人芳香二烷基磷酸酯酶基因丛基因多态性快速分析法 摘要 :目的 建立一种人芳香二烷基磷酸酯酶(PON)基因丛等位基因快速分型法。方法 在Multiplex-PCR -RELP 基础上,通过引物设计错配,在一体系中同时扩增分别含PON1-192、PON1
An Emulsion Polymerase Chain ReactionBased Method for Molecular Haplotyping
where LD is limited, especially when the polymorphisms in question affect the function of a single gene product. We have illustrated this technology with the human paraoxonase 1 gene (PON1), where polymorphisms affecting transcription and enzymatic activity
Linking Emulsion PCR Haplotype Analysis
of the markers. LE-PCR is illustrated for polymorphisms in human paraoxonase 1 (PON1 ) that have been shown to affect transcriptional activity and substrate specificity in the detoxification of organophosphates.
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