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文献和实验Isolation of Proteins Associated with the DNA-Bound Estrogen Receptor
of proteins associated with the DNA-bound estrogen receptor α (ERα) using an agarose-based electrophoretic mobility shift assay (EMSA). This method should be readily adapted to a variety of cultured cell lines, DNA sequences, and transcription factors
Estrogen Receptor mRNA In Situ Hybridization Using Microprobe System
of this family, including their subtypes have been cloned and characterized. For instance, until the recent cloning of a second estrogen receptor (ER) α, ERβ had been considered as the only receptor able to bind estrogen with high affinity. ERα protein is smaller
对儿茶酚胺反应的受体,有α和β二类,α受体是其中一种。α受体一般表现兴奋性反应,儿茶酚胺与α受体作用可引起血管、子宫、输精管等的平滑肌收缩。阻断这一反应的药物为α阻断剂,有麦角碱、地苯那明(Dibenamine,双苄胺)、苯氧基苯胺等。
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