- 询价
- Promab
- 美国
- PMB-B00020
- 2025年07月13日
- Recombinant human PD-1-Fc protein
- 66
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
CHO cells
- 亚型：
Recombinant human PD-1-Fc protein
- 形态：
Flow cytometry, animal model study
- 保存条件：
Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
- 克隆性：
Recombinant human PD-1-Fc protein
- 标记物：
Flow cytometry, animal model study
- 适应物种：
Human
- 保质期：
CHO cells
- 抗原来源：
Recombinant human PD-1-Fc protein
- 目录编号：
Flow cytometry, animal model study
- 级别：
77
- 库存：
10
- 供应商：
艾美捷科技
- 宿主：
66
- 应用范围：
Recombinant human PD-1-Fc protein
- 浓度：
55
- 靶点：
CHO cells
- 抗体英文名：
Nivolumab Biosimilar, Human PD-1 Monoclonal Antibody
- 抗体名：
Nivolumab 生物类似药, 人 PD-1 单克隆抗体
Nivolumab 生物类似药, 人 PD-1 单克隆抗体，Nivolumab Biosimilar, Human PD-1 Monoclonal Antibody，Nivolumab Biosimilar, Human PD-1 Monoclonal Antibody,Nivolumab 生物类似药, 人 PD-1 单克隆抗体
产品名称：-In vivo级抗体试剂
产品货号：PMB-B00020
产品规格：询价/1mg/5mg/20mg
应用类型：Flow cytometry, animal model study
What is Nivolumab biosimilar research grade? Nivolumab is a humanized IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation S228P for additional stability and reduced variability. Nivolumab Biosimilar uses the same protein sequences as the therapeutic antibody nivolumab.PD-L1 and PD-L2 (B2-DC or CD273, programmed cell death ligand 2) are the two ligands for the receptor PD-1 (CD279, programmed cell death protein 1).Nivolumab blocks PD-1 inhibitory signalling to T-cells. It has a long duration of action as it is administered every 2-4 weeks. Patients should be counselled regarding the risk of immune-mediated adverse effects, infusion-related adverse effects, complications of allogenic hematopoietic stem cell transplants, embryo-fetal toxicity.The ligands PD-L1 and PD-L2 bind to the PD-1 receptor on T-cells, inhibiting the action of these cells. Tumor cells express PD-L1 and PD-L2. Nivolumab binds to PD-1, preventing PD-L1 and PD-L2 from inhibiting the action of T-cells, restoring a patient's tumor-specific T-cell response.
-In vivo级抗体试剂Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
点击：-In vivo级抗体试剂更多Promab产品信息价格，货期，产品说明，百度搜“艾美捷科技”进入官网网站，查看具体产品且快速下单。
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