1,2,3,4,6,7,8-Heptachlorodiben

多氯二苯并二恶英；诱导原代人类外周血淋巴细胞中CYP1A1、CYP1B1和AHRR的表达；增加分离的人类外周血淋巴细胞中的EROD活性；在100µg/kg剂量下降低小鼠体内针对绵羊红细胞的抗体产生；长期服用可缩短大鼠的死亡时间并增加肺和肝肿瘤的发生率；已在淡水鱼、人类母乳和城市垃圾焚烧炉附近的空气中发现。A polychlorinated dibenzodioxin; induces the expression of CYP1A1, CYP1B1, and AHRR in primary human peripheral blood lymphocytes; increases EROD activity in isolated human peripheral blood lymphocytes; decreases the production of antibodies against sheep red blood cells in mice at 100 µg/kg; chronic administration decreases the time to death and increases lung and liver tumorigenesis in rats; has been found in freshwater fish, human breastmilk, and in the air near municipal waste incinerators.分子式C12HCl7O2分子量425.3ClC1=C(Cl)C=C2OC3=C(C(Cl)=C(C(Cl)=C3Cl)Cl)OC2=C1Cl