PUMA BH3 (human) (trifluoroace

Bak的肽激活剂；与Bak结合（HEPES和CHAPS缓冲液中的Kds分别为290和26nM）并诱导Bak同源寡聚化和Bak介导的膜通透性。A peptide activator of Bak; binds to Bak (Kds = 290 and 26 nM in HEPES and CHAPS buffer, respectively) and induces Bak homo-oligomerization and Bak-mediated membrane permeabilization.分子式C128H202N42O43S • XCF3COOH分子量3049.3[H]N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(O)=O)C(N[C@]([C@H](CC)C)([H])C(NCC(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)CC1=CC=C(O)C=C1)=O)=O)C)=O)=O)=O)CC(O)=O)=O)CC(O)=O)=O)C)=O)CCSC)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)C)=O)CC2=CNC3=C2C=CC=C3)=O)=O)=O.OC(C(F)(F)F)=O