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- 爱必信(Absin)
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- 2025年07月14日
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文献和实验Introduction of human 14-3-3 proteins
with several tyrosine-phosphorylated proteins and phosphatidylinositol 3-kinase (PI3-K)in T cells.We report here the identification of the 120-kDa 14-3-3tau-binding phosphoprotein present in activated T cell lysates as Cbl,a protooncogene product of unknown function
, leading to expression of the protooncogenes c-Fos, c-Jun, and Elk1. The Syk, that is responsible for c-Myc gene induction, initiates the second pathway. The final pathway results in BCL2 (B-Cell Leukemia-2) expression, and progression through a Rho, PI
complex by examining the effects of deletion of the REG1 gene on the yeast phosphoproteome. In S. cerevisiae , PP-1 (Glc7p) and its binding protein, Reg1p, are essential for the regulation of glucose repression pathways. The target for this phosphatase
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