- 询价
- 辰辉创聚生物
- 中国
- NBL-242700
- 2025年07月13日
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- 详细信息
- 技术资料
- 保存条件：
Short term 4℃; Long term -20℃.
- 保质期：
见COA
- 英文名：
Recombinant Mouse EREG, hFc-tag
- 库存：
大量
- 供应商：
北京辰辉创聚生物技术有限公司
- 规格：
100ug;1mg;Bulk
| 产品信息
品名:NebuSelect™ Recombinant Mouse EREG, hFc-tag
货号:NBL-242700
品牌:Nebulabio
规格:100ug；1mg；Bulk
| 产品描述
NebuSelect™ Recombinant Mouse EREG, hFc-tag(Cat#NBL-242700) is expressed in HEK293 with hFc tag at the N-Terminus.It contains Val56-Leu101.
| 产品属性
表达系统:HEK293
标签:hFc-tag
靶点名称:EREG
物种：Mouse
分子量：The protein has a predicted MW of 32.7 kDa. Due to glycosylation, the protein migrates to 37-40 kDa based on Bis-Tris PAGE result.
氨基酸序列：Val56-Leu101
Accession: Q61521
纯度:＞95%
内毒素：＜1EU/ug(LAL Method)
储存运输条件: Short term 4℃; Long term -20℃.
| 靶点信息
Epidermal growth factor receptor (EGFR) regulates many crucial cellular programs, with seven different activating ligands shaping cell signaling in distinct ways.EGFR ligands epiregulin (EREG) and epigen (EPGN) stabilize different dimeric conformations of the EGFR extracellular region. As a consequence, EREG or EPGN induce less stable EGFR dimers than EGF-making them partial agonists of EGFR dimerization. Unexpectedly, this weakened dimerization elicits more sustained EGFR signaling than seen with EGF, provoking responses in breast cancer cells associated with differentiation rather than proliferation.
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