- 询价
- 辰辉创聚生物
- 中国
- NBL-242297
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Short term 4℃; Long term -20℃.
- 保质期：
见COA
- 英文名：
Recombinant Human MMP-2 (pro form), His-tag
- 库存：
大量
- 供应商：
北京辰辉创聚生物技术有限公司
- 规格：
100ug;1mg;Bulk
| 产品信息
品名:NebuSelect™ Recombinant Human MMP-2 (pro form), His-tag
货号:NBL-242297
品牌:Nebulabio
规格:100ug；1mg；Bulk
| 产品描述
NebuSelect™ Recombinant Human MMP-2 (pro form), His-tag(Cat#NBL-242297) is expressed in HEK293 with His tag at the N-Terminus.It contains Ile34-Cys660.
| 产品属性
表达系统:HEK293
标签:His-tag
靶点名称:MMP-2
物种：Human
分子量：The protein has a predicted MW of 71.6 kDa. Due to glycosylation, the protein migrates to 72-75 kDa based on Bis-Tris PAGE result.
氨基酸序列：Ile34-Cys660
Accession: P08253
纯度:＞95%
内毒素：＜1EU/ug(LAL Method)
储存运输条件: Short term 4℃; Long term -20℃.
| 靶点信息
Matrix metalloproteinase (MMP)-2 cleaves a broad spectrum of substrates, including extracellular matrix components (responsible for normal tissue remodeling) and cytokines (modulators of the inflammatory response to physiological insults such as tissue damage). MMP-2 expression is elevated in many cardiovascular pathologies (e.g., myocardial infarction, hypertensive heart disease) where tissue remodeling and inflammatory responses are perturbed.
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文献和实验Human synovial cells in culture, particularly those obtained from patients with rheumatoid arthritis, secrete a number of matrix metalloproteinases (MMPs) into the culture medium. Enzymes secreted include collagenases (MMP-1, MMP-13
matrix degradation by MMPs even if the enzymes are in the active form. Although biochemical studies can determine net MMP activity they do not provide any localizational information and activation of MMPs may occur during disruption of the tissue sample
Expression of Recombinant Matrix Metalloproteinases in Escherichia coli
-3, matrilysin, elastase, collagenase-1, collagenase-3, neutrophil collagenase, and membrane type-1 MMP (1 –20 ). The expression of a truncated form of human stromelysin-1 (SL-1) will be used to illustrate the methods utilized for the expression of a matrix
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