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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
保存于-209℃
- 保质期:
一年
- 英文名:
Human Pro-MMP-9
- 库存:
一定量库存
- 供应商:
美国ABBIOTEC公司
- 规格:
0.01 mg
Matrix metalloproteinases are a family of zinc- and calcium-dependant endopeptidases, which degrade extracellular matrix proteins. Matrix metalloproteinase 9 (MMP-9) is secreted as a 92-kDa zymogen (pro-MMP-9) cleaved into the 82-kDa active enzyme. MMP-9 has a gelatin-binding domain consisting of three fibronectin type II units, a catalytic domain containing the zinc-binding site, a proline-rich type V collagen-homologous domain, and a hemopexin-like domain. MMP-9 is produced by monocytes, macrophages, neutrophils, keratinocytes, fibroblasts, osteoclasts and endothelial cells, and is involved in inflammatory responses, tissue remodeling, wound healing, tumor growth, and metastasis. Recombinant human Pro-MMP-9 comprises a 688 aa fragment (20-707) corresponding to the pro form of the protein minus the signal peptide and is expressed in E. coli with an amino-terminal hexahistidine tag.
形 态 :
Each vial contains 0.01 mg protein (liquid) in PBS pH7.4, 50% glycerol. Final concentration 0.1-1 mg/ml.
来 源 :
E. coli
别 名 :
Pro-MMP-9; Matrix metalloproteinase 9; gelatinase B; 92kD gelatinase; 92kD type IV collagenase precursor; CLG4B; GELB
纯 度 :
Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.
分子量 :
78.59 kDa
应 用 :E, WB
保存条件 :
Store at -20°C. Product is guaranteed one year from the date of shipment.
产品链接 :http://www.abbiotec.com/proteins/human-pro-mmp-9
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