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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide corresponding to the C-terminal region of human STAT1.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
ERB0201
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
Elucigen Biosciences
- 宿主:
Rabbit
- 应用范围:
ICC, WB
- 浓度:
0.5 mg/mL
- 靶点:
P42224
- 抗体英文名:
Anti-STAT1 (α & β) Recombinant Rabbit Monoclonal Ab
- 抗体名:
Anti-STAT1 (α & β) Recombinant Rabbit Monoclonal Ab
- 规格:
25μg/100μg/500μg
| 规格: | 25μg | 产品价格: | ¥860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | 询价 |
| 规格: | 500μg | 产品价格: | 询价 |
STAT1 (Signal Transducer and Activator of Transcription 1) is a transcription factor that plays a crucial role in mediating the cellular response to cytokines and growth factors. It exists in two isoforms, STAT1α and STAT1β, which are generated by alternative splicing. STAT1α is the full-length form and is primarily involved in immune responses, particularly in the activation of genes in response to interferons (IFNs), which are key regulators of antiviral defense and immune signaling. STAT1β, the shorter isoform, lacks the transactivation domain and has a more regulatory role, often modulating the activity of STAT1α. Both isoforms are essential for proper immune function, and mutations in STAT1 can lead to immune deficiencies and increased susceptibility to infections. Research on STAT1 focuses on its role in immune regulation, host defense, and its involvement in various diseases, including autoimmune disorders and cancers.
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文献和实验该产品被引用文献
Durbin, J.E. et al. (1996) Cell 84, 443-50.
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Anti-STAT1 (α & β) Recombinant Rabbit Monoclonal Ab
¥860





