Anti-p44 MAPK / Erk1 Recombina

p44 MAPK, also known as ERK1 (Extracellular signal-Regulated Kinase 1), is a critical member of the mitogen-activated protein kinase (MAPK) signaling pathway. It plays a key role in regulating cellular processes such as growth, differentiation, proliferation, and survival. p44 MAPK is activated by various extracellular signals, including growth factors and stress stimuli, through a kinase cascade. Once activated, p44 MAPK translocates to the nucleus, where it phosphorylates a variety of transcription factors, influencing gene expression. Dysregulation of p44 MAPK signaling is implicated in a variety of diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders, making it a significant target for therapeutic interventions.