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Anti-p44 MAPK / Erk1 Recombina

nt Rabbit Monoclonal Ab
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  • ¥860
  • Elucigen Biosciences
  • ERB0030
  • 2025年08月13日
  • ICC, IHC, WB
  • Rabbit
  • Human, Mouse, Rat
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Synthetic peptide corresponding to the C-terminal region of rat p44MAPK.

    • 亚型

      IgG

    • 形态

      Liquid

    • 保存条件

      -20°C

    • 克隆性

      Monoclonal

    • 标记物

      Unconjugated

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      12 months from the shipping date of the product.

    • 抗原来源

      Human

    • 目录编号

      ERB0030

    • 级别

      Primary Antibodies

    • 库存

      Available

    • 供应商

      Elucigen Biosciences

    • 宿主

      Rabbit

    • 应用范围

      ICC, IHC, WB

    • 浓度

      0.5 mg/mL

    • 靶点

      P21708

    • 抗体英文名

      Anti-p44 MAPK / Erk1 Recombinant Rabbit Monoclonal Ab

    • 抗体名

      Anti-p44 MAPK / Erk1 Recombinant Rabbit Monoclonal Ab

    • 规格

      25μg/100μg/500μg

    规格:25μg产品价格:¥860.0
    规格:100μg产品价格:询价
    规格:500μg产品价格:询价
    p44 MAPK, also known as ERK1 (Extracellular signal-Regulated Kinase 1), is a critical member of the mitogen-activated protein kinase (MAPK) signaling pathway. It plays a key role in regulating cellular processes such as growth, differentiation, proliferation, and survival. p44 MAPK is activated by various extracellular signals, including growth factors and stress stimuli, through a kinase cascade. Once activated, p44 MAPK translocates to the nucleus, where it phosphorylates a variety of transcription factors, influencing gene expression. Dysregulation of p44 MAPK signaling is implicated in a variety of diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders, making it a significant target for therapeutic interventions.

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    图标文献和实验
    该产品被引用文献
    Marais, R. et al. (1993) Cell 73, 381-93.
    相关实验
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      :使用 Anti-phospho-Akt (Ser473) Rabbit mAb 对石蜡包埋的人乳腺癌组织进行免疫组织化学分析。(图 A)使用免疫组化试剂盒M&R HRP/DAB Detection IHC Kit,抗体 1:100 稀释;(图 B) 采用普通免疫组化试剂盒,抗体 1:25 稀释。 图 6 免疫组化实验检测 Erk1/2 表达 注:使用 Anti-Erk1/2 Mouse mAb与p44/42 MAPKErk1/2)Rabbit mAb 对正常小鼠心脏组织进行免疫

    • Detection of ERK1/2 Activities Using Affinity Reagents

      The three major mammalian mitogen-activated protein kinase (MAPK) subfamilies include the extracellular signal-regulated kinases (ERK1/2), the c-Jun N-terminal kinases (JNKs), and the p38 kinases. These kinases are differentially activated

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    文献支持
    Anti-p44 MAPK / Erk1 Recombinant Rabbit Monoclonal Ab
    ¥860