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- CAS号：
3862-25-7
7α-Hydroxy-4-cholesten-3-one
3862-25-7
C₂₇H₄₄O₂
400.64
White to Off-White Solid
Chloroform (Slightly), Methanol (Slightly)
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文献和实验7α-Hydroxy-4-cholesten-3-one
3862-25-7
C₂₇H₄₄O₂
400.64
White to Off-White Solid
Chloroform (Slightly), Methanol (Slightly)
. This method is based on the conversion of the primary cytochrome P450 metabolite, 7α-hydroxycholesterol, into 7α-hydroxy-4-cholesten-3-one in a reaction catalyzed by exogenous cholesterol oxidase, followed by chromatographic separation with monitoring at 254
for the determination of cholesterol 7α-hydroxylase acttvity based on the conversion by cholesterol oxidase of the primary P450 metabohte 7α-hydroxycholesterol to 7α-hydroxy-4-cholesten-3-one, which can be detected at 254 nm.
CarbonCarbon Bond-Forming Enzymes for the Synthesis of Non-natural Amino Acids
An enzymatic methodology for the preparation of β-hydroxy-α-amino acid derivatives is described. The method consists of the stereoselective aldol addition reaction of glycine to N -Cbz-amino aldehydes furnishing 3-hydroxy-2,4-diaminobutyric
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