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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Short term 4℃; Long term -20℃.
- 保质期:
见COA
- 英文名:
Recombinant Human GCGR/Glucagon receptor, Avi-His-tag
- 库存:
大量
- 供应商:
北京辰辉创聚生物技术有限公司
- 规格:
100ug;1mg;Bulk

| 产品信息
品名:NebuSelect™ Recombinant Human GCGR/Glucagon receptor, Avi-His-tag
货号:NBL-241124
品牌:Nebulabio
规格:100ug;1mg;Bulk
| 产品描述
NebuSelect™ Recombinant Human GCGR/Glucagon receptor, Avi-His-tag(Cat#NBL-241124) is expressed in HEK293 with His tag and Avi tag at the C-terminus.It contains Ala26-Lys136.
| 产品属性
表达系统:HEK293
标签:Avi-His-tag
靶点名称:GCGR/Glucagon receptor
物种:Human
分子量:The protein has a predicted MW of 15.96 kDa. Due to glycosylation, the protein migrates to 30-50 kDa based on Bis-Tris PAGE result.
氨基酸序列:Ala26-Lys136
Accession: P47871
纯度:>95%
内毒素:<1EU/ug(LAL Method)
储存运输条件: Short term 4℃; Long term -20℃.
| 靶点信息
The pancreatic hormone glucagon activates the glucagon receptor (GCGR), a class B seven-transmembrane G protein-coupled receptor that couples to the stimulatory heterotrimeric G protein and provokes PKA-dependent signaling cascades vital to hepatic glucose metabolism and islet insulin secretion. The GCGR expressed at the plasma membrane is constitutively ubiquitinated and upon agonist-activation, internalized GCGRs are deubiquitinated at early endosomes and recycled via Rab4-containing vesicles.
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文献和实验三句话读懂一篇 CNS:橙子可甜可酸的原因;吃红肉促进结直肠癌发生的分子机制...
论文 Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor,首次报道了 Compound 2 结合 GLP-1R 的三个高分辨率冷冻电镜结构,突破技术瓶颈, 揭示了该受体变构激动调节的分子机制,为拓展受体药理学内涵和相关药物发现提供了重要的结构基础。 图 10. 来源 Nature Communications 本周推荐:三句话读懂一篇 CNS:男性的大脑和睾丸相似;父亲熬夜,影响
. N 6-methyladenosine modification-mediated mRNA metabolism is essential for human pancreatic lineage specification and islet organogenesis. Nature Communications, 2022, 13.1: 4148. 【5】Zhu S, Russ H A, Wang X, et al. Human pancreatic beta-like cells
CD11a/CD11b/CD11c 分子 CDlla 常用单克隆抗体或代号:MHM24, 2F12; CRIS―3(LFA―lα链,整合素α1) 主要表达细胞:Leu[A5] 分子质量(kDa)和结构:spl80(整合素α) 功 能:与1CAM-l(CD54)、ICAM-2(CDl02)、ICAM-3(C1350)结合,介导细胞黏附;与JAMl结合,参与白细胞穿过内皮细胞
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