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- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
BMS-303141
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
943962-47-8
纯度：98% by TLC；NMR (Conforms)
分子式：C19H15Cl2NO4S
分子量：424.30
溶剂：DMSO (25 mg/ml) Ethanol (20 mg/ml)
性状：White solid
存储：-20°C
Activity (short version)：ATP citrate lyase (ACL) inhibitor
Function / Pharmacology：Potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 M. Inhibits lipid biosynthesis, IC50=8 M in HepG2 cells.1,2 Reduces weight gain, lowers plasma cholesterol, triglycerides and glucose in high-fat-fed mice.2 A novel tool compound for exploring the potential of ACL inhibition as a target for metabolic disorders such as obesity and dyslipidemia.2 Impairs proliferation or induces death in androgen-depleted castration resistant prostate cancer cells.3 Reduces cell cycle progression in iBN cells.4
分子式：C19H15Cl2NO4S
分子量：424.30
溶剂：DMSO (25 mg/ml) Ethanol (20 mg/ml)
性状：White solid
存储：-20°C
Activity (short version)：ATP citrate lyase (ACL) inhibitor
Function / Pharmacology：Potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 M. Inhibits lipid biosynthesis, IC50=8 M in HepG2 cells.1,2 Reduces weight gain, lowers plasma cholesterol, triglycerides and glucose in high-fat-fed mice.2 A novel tool compound for exploring the potential of ACL inhibition as a target for metabolic disorders such as obesity and dyslipidemia.2 Impairs proliferation or induces death in androgen-depleted castration resistant prostate cancer cells.3 Reduces cell cycle progression in iBN cells.4
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文献和实验该产品被引用文献
943962-47-8
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BMS-303141
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