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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
冷冻-20℃
- 英文名：
Monophosphoryl 3-Deacyl Lipid A Pat No. 9,241,988
- 库存：
999+
- 供应商：
上海维亦特生物科技有限公司
- CAS号：
1699735-79-9
别名：Monophosphoryl 3-Deacyl Lipid A Pat No. 9,241,988
分子式：C82H158N3O20P
分子量：1537.114
稳定性：1 Years
存储：冷冻-20°C
溶解性：Solubility in Different SolventsSoluble in ethanol at 1mg/mL, soluble in DMSO at 5mg/mL, soluble in Chloroform:Methanol:Water at 5mg/mL, insoluble in water (aqueous buffers, serum etc.); however, it can be dispersed in an aqueous medium using a suitable emulsifier or detergent. This species is soluble in chloroform (at least up to 50 mg/mL) and chloroform:methanol solvent systems, however gentle heating and sonication may be necessary to aid in dissolution. Dropwise additions of methanol or water may aid dissolution in chloroform at higher concentrations. If using in combination with other lipids, dissolve this lipid separately and then combine dissolved lipids in their respective solvent solutions.
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文献和实验DNA Immunization in Combination with the Immunostimulant Monophosphoryl Lipid A
The use of the MPL� immunostimulant, a monophosphoryl lipid A preparation derived from the lipopolysaccharide (LPS) of Salmonella minnesota R595, began with the studies of Johnson et al. (1 ). It was shown that LPS was a potent adjuvant
Preclinical Development of AS04
focuses on the methods that were used during the preclinical evaluation of AS04. AS04 consists of the combination of aluminum salts and 3′ -O -deacylated monophosphoryl lipid A (MPL), a detoxified lipid A derivative with retained immunostimulatory capa
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