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- 详细信息
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- 文献和实验
- 技术资料
- 英文名：
TPC-1 Human Papillary Thyroid Carcinoma Cell line
- 规格：
T25/冻存管
细胞名称：TPC-1 Human Papillary Thyroid Carcinoma Cell line
货号：SCC147
种属：human
细胞系描述：Cancer Cells
应用：
Research Category
Cancer
Oncology
TPC-1 human papillary thyroid carcinoma cell line is a highly characterized model for thyroid cancer research.
This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation.
质量：
• Each vial contains ≥ 1X10⁶ viable cells.
• Cells are tested negative for infectious diseases by a Human Essential CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are negative for mycoplasma contamination.
• Cells are verified to be of human origin and negative for inter-species contamination from mouse, rat, chinese hamster, Golden Syrian hamster, and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.
• Each lot of cells is genotyped by STR analysis to verify the unique identity of the cell line.
储存及稳定性：Store in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
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文献和实验Liu C, Wang J, Zhao L, He H, Zhao P, Peng Z, Liu F, Chen J, Wu W, Wang G, Dong F. Knockdown of Thymidine Kinase 1 Suppresses Cell Proliferation, Invasion, Migration, and Epithelial-Mesenchymal Transition in Thyroid Carcinoma Cells. Front Oncol. 2020 Jan 29;9:1475. doi: 10.3389/fonc.2019.01475. PMID: 32064235; PMCID: PMC7000458.
Raman R, Villefranc JA, Ullmann TM, Thiesmeyer J, Anelli V, Yao J, Hurley JR, Pauli C, Bareja R, Wha Eng K, Dorsaint P, Wilkes DC, Beg S, Kudman S, Shaw R, Churchill M, Ahmed A, Keefer L, Misner I, Nichol D, Gumpeni N, Scognamiglio T, Rubin MA, Grandori C, Solomon JP, Song W, Mosquera JM, Dephoure N, Sboner A, Elemento O, Houvras Y. Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer. J Exp Med. 2022 Jun 6;219(6):e20210390. doi: 10.1084/jem.20210390. Epub 2022 May 5. PMID: 35510953; PMCID: PMC9082625.
Lu H, Chen S, You Z, Xie C, Huang S, Hu X. PFKFB4 negatively regulated the expression of histone acetyltransferase GCN5 to mediate the tumorigenesis of thyroid cancer. Dev Growth Differ. 2020 Feb;62(2):129-138. doi: 10.1111/dgd.12645. Epub 2020 Jan 7. PMID: 31912488.
Panebianco F, Nikitski AV, Nikiforova MN, Nikiforov YE. Spectrum of TERT promoter mutations and mechanisms of activation in thyroid cancer. Cancer Med. 2019 Oct;8(13):5831-5839. doi: 10.1002/cam4.2467. Epub 2019 Aug 13. PMID: 31408918; PMCID: PMC6792496.
