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- 库存:
100
- 供应商:
无锡莱弗思生物实验器材有限公司
- 规格:
10 μL
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文献和实验Characterisation of Viral Proteins that Inhibit Toll-Like Receptor Signal Transduction
Toll-like receptor (TLR) signalling involves five TIR adapter proteins, which couple to downstream protein kinases that ultimately lead to the activation of transcription factors such as nuclear factor-κB (NF-κB) and members of the interferon
【进展|热点】PD-1信号通过上调BATF抑制HIV特异性CD8阳性T细胞的功能
,探寻到3个特异性表达上调的转录因子:BATF, signal transducer and activator of transcription-1 (STAT1)和interferon regulatory factor-9 (IRF9)。采用构建BATF过表达载体转染T细胞,并应用siRNA策略考察BATF蛋白对T细胞分泌相应细胞因子能力的影响,深入探讨了BATF分子的生物学功能及其与HIV特异性T细胞活性之间的关系。文章认为,PD-1介导的抑制性信号除了可以降低TCR传导的特异性刺激信号
【申请上传】Current Protocols in Immunology
, Erythropoietin, Steel Factor, and Flt-3 Ligand Unit 6.5 Measurement of Mouse and Human Interleukin 5 Unit 6.6 Measurement of Interleukin 6 Unit 6.7 Measurement of Interleukin 7 Unit 6.8 Measurement of Mouse and Human Interferon Unit 6.9 Measurement
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